HYAFLEX for SMALL ANIMALS

VARIETY is how we give you a healthy way to add more good years for your loving pets with HyaFlex. We took in consideration that people are not the only ones who need to lose weight or be healthy.

DID you know that 1 out of every 4 pets may need joint health support?

This is unfortunate because your pet cannot tell you when and if they hurt. It can be difficult to know when your pet is having problems. However, we do know that perception is common to both humans and animals, so observing your pet's behavior is the key to recognizing possible discomforts.

Nobody knows your pet like you do. You are the most important element when it comes to understanding joint health in your pet.

Were they slow to move? Do they tire easily or have difficulty climbing stairs? Are they sensitive to touch and become aggressive?

If any of these are recognizable in your pet, your pet may be experiencing some type of joint disorder.

Support healthy joints and helps alleviate the joint pain associated with normal daily exercise and activity. HyaFlex™ is hyaluronic acid, a special mucopolysaccharide that is found naturally in animals and its function in the the body is, amongst other things, to lubricate movable parts, such as joints and muscles. Hyaluronic acid has been known to be effective in supporting healthy joints in horses and humans. Hyaluronic acid restores proper lubrication, joints are less stiff and pets regain full movement. HyaFlex™ has been helping pets to regain their quality of life but most importantly, it allows you to regain another member of your active family.

About HyaFlex™

Benefits of Hyaluronic Acid:

• Helps alleviate the joint pain associated with normal daily exercise and activity
• Lubricates the joint
• Reduces joint friction
• Supports healthy joints
• Healthier skin

Four Reasons to Try HyaFlex™:   

High Quality
The hyaluronic acid in HyaFlex™ is one of the purest and highest in molecular weight of any oral hyaluronic acid products on the market today. Higher molecular weight acid can hold more water, has better lubrication properties and better shock absorbing properties than low molecular weight hyaluronic acid.

Patented
The only patented oral hyaluronic acid for supporting healthy joint function.
US PATENT # 6,607,745

Easy to Administer
HyaFlex™ is a tasteless liquid solution unlike competitive joint products. Each bottle of HyaFlex™ provides a 30-60 day supply (depending on the weight of the small animal).

Producing Results
Animal owners and veterinarians are reporting the many benefits of HyaFlex™.

Hyaluronic acid is used in humans and horses, so it's only natural to bring these benefits to man's best friend!

Understanding Joint Health:

Recognizing the Signs:
The key is to look for a change of behavior in your pet. Need for joint health support will become more apparent as time goes on.

It is important to observe pets closely;

• Decreased activity?

• Reluctance to walk, run, jump or play?

• Lagging behind on walks?

• Stiffness?

• Limping?

• Difficulty rising from a resting position?

• Soreness when touched?

• Acting aggressive or withdrawn?

• Exhibiting other personality changes?

If you notice any of these changes, consult your veterinarian. The sooner the condition is recognized, the sooner your pet can be active again!

Understanding Joint Anatomy:

To understand arthritis, one must become familiar with the anatomy of a healthy functioning joint. Let's start off with the understanding the joint capsule. The joint capsule is a thick fibrous tissue that connects the bones, provides the outer layer of the joint and holds the fluid inside the joint cavity. The muscles serve to support the joint capsule and to provide joint movement. The tendon is an elastic cord that attaches the muscle to the bone and assist with movement. The synovial membrane is the inner lining of the joint capsule. It is highly vascularized and therefore is responsible for carrying nutrients to the joint and most importantly, producing the synovial fluid.

The synovial fluid is a clear viscous fluid that lubricates the joints. It consists of blood plasma and hyaluronic acid. Without it, joint movement would be limited and articular cartilage becomes vulnerable. The cartilage covers the ends of the bones and absorbs most of compression and stress in the joint. Because it is a slippery material, it allows the joints to move smoothly and easily.

Overall, the parts of the joint have to work together, but the two most important parts are the synovial fluid which provides the lubrication for the joint and the cartilage, which absorbs the stress. When these two are damaged, problems are unavoidable.

How Vets Recognize Problems:

1. First your vet will evaluate the case history of your pet. As part of this background your vet may ask you several questions about your pet's care and activities to determine a potential cause of the joint problem.

2. Next your vet will do a physical examination of your pet. This usually involves palpating the areas of concern. Most vets are very skilled with their hands and can often feel if a joint is inflamed and swollen.

3. The veterinarian will inspect your pet at a walk and run. They will walk them in a straight line watching for any lameness.

4. Your veterinarian may perform a flexion text. This is done by bending the joint and holding for at least one minute and then released. After a joint is released, the pet is observed while walking and running. Often time this will exaggerate the lameness and make it more clearly visible during activity.

5. It may be necessary to perform a radiographic x-ray examination to get visual representation of what may be causing the lameness.

6. Your veterinarian may remove by needle some of the synovial fluid located in the joint to determine if an infection is present.

Deterring Joint Problems:

Older pets have a variety of lameness problems due to a number of environmental stressors, but you can help relieve some of these stresses by:

1. Avoiding obesity and heavy loads

2. Providing your pet with suitable bedding

3. Avoiding quick changes in duration or intensity of exercise

4. Avoid hard and unstable ground surfaces

5. Feeding a diet high in protein and other nutrients. Joints can never heal or become stronger without proper nutrition.

In Summary..

Pet owners should become very familiar with recognizing joint health in their pets. Because joint problems are progressive, acting early can give your pet a better chance at getting back to their normal activities such as walking and running. Often times injury to the joint is far past repair and it is quite likely that the animal will never regain normal movement.

The Anti-aging formula for overall joint and skin health

HA is a special mucopolysacharide that is the normal lubricant in small animals' joints. When present in the joint, even a joint with minimal or no cartilage, it can provide a cushion effect. As your pet's body ages, it produces less and less HA. The joints may become stiff, the skin dry and wrinkled.

Hyaluronic Acid replacement, referred to as viscosupplementation, is done by injecting HA directly into the affected joints. Although successful, it is very expensive, and yet only effective in the areas injected. Now, the high molecular weight HA found in HyaFlex™, a convenient oral solution, presents an easier and far more affordable way to replace the HA that your pet has lost. It also provides benefits to their entire body! Read our testimonials to see for yourself. Pets are experiencing results noticeable in a short period of time, plus a variety of beneficial effects -- from softer coat, to clearer and healthy eyes, even anti-aging properties.

Hyaluronic Acid (HA) was first used commercially in 1942 when Endre Balazs applied for patent to use it as a substitute for egg white in bakery products. He went on to become the leading expert on HA, and made the majority of discoveries concerning HA during the next 50 years.

In the last two decades, the uses of hyaluronic acid have been extended to a number of areas, including orthopedics, use in fertility clinics, and tissue augmentation. In the pst few years, biotechnology has been used to develop hyaluronic acid derivatives with tailor-made molecular sizes, which will further increase the potential applications of this remarkable molecule. Hyaluronic Acid is Nature's Moisturizer!

List of Resources about hyaluronic acid:

1. Marshall KW. Viscosupplementation for osteoarthritis: current status, unresolved issues and future directions. J Rheumatol 1998;25:2056-8.

2. George E. Intra-articular hyaluronan treatment for osteoarthritis. Ann Rheum Dis 1998;57:637-40.

3. Wobig M, Bach G, Beks P, Dickhut A, Runzheimer J, Schwieger G, et al. The role of elastoviscosity in the efficacy of viscosupplementation for osteoarthritis of the knee: a comparison of hylan G-F 20 and a lower-molecular-weight hyaluronan. Clin Ther 1999;21:1549-62.

4. Cohen MD. Hyaluronic acid treatment (viscosupplementation) for OA of the knee. Bull Rheum Dis 1998;47:4-7.

5. Balazs EA, Denlinger JL. Viscosupplementation: a new concept in the treatment of osteoarthritis. J Rheumatol 1993;20(suppl 39):3-9.

6. Weiss C, Balazs EA, St. Onge R, Denlinger JL. Clinical studies of the intraarticular injection of HealonR (sodium hyaluronate) in the treatment of osteoarthritis of human knees. Osteoarthritis symposium. Palm Aire, Fla., October 20-22, 1980. Semin Arthritis Rheum. 1981;11(suppl 1):143-4.

7. Peyron JG. Intraarticular hyaluronan injections in the treatment of osteoarthritis: state-of-the-art review. J Rheumatol 1993;39(suppl):10-5.

8. Henderson EB, Smith EC, Pegley F, Blake DR. Intra-articular injections of 750 kD hyaluronan in the treatment of osteoarthritis: a randomised single centre double-blind placebo-controlled trial of 91 patients demonstrating lack of efficacy. Ann Rheum Dis 1994;53:529-34.

9. Lohmander LS, Dalen N, Englund G, Hamalainen M, Jensen EM, Karlsson K, et al. Intra-articular hyaluronan injections in the treatment of osteoarthritis of the knee: a randomised, double blind, placebo controlled multicentre trial. Hyaluronan Mulicentre Trial Group. Ann Rheum Dis 1996;55:424-31.

10. Dougados M, Nguyen M, Listrat V, Amor B. High molecular weight sodium hyaluronate (hyalectin) in osteoarthritis of the knee: a 1 year placebo-controlled trial. Osteoarthritis Cart 1993;1:97-103.

11. Marshall KW. Viscosupplementation for osteoarthritis: current status, unresolved issues and future directions. J Rheumatol 1998;25:2056-8.

12. Listrat V, Ayral X, Paternello F, Bonvarlet JP, Simonnet J, Amor B, et al. Arthroscopic evaluation of potential structure modifying activity of hyaluronan (Hyalgan) in osteoarthritis of the knee. Osteoarthritis Cart 1997;5:153-60.

13. Altman RD, Moskowitz R. Intraarticular sodium hyaluronate (Hyalgan) in the treatment of patients with osteoarthritis of the knee: a randomized clinical trial. J Rheumatol 1998;25:2203-12 [Published erratum appears in J Rheumatol 1999;26:1216].

14. Wobig M, Dickhut A, Maier R, Vetter G. Viscosupplementation with hylan G-F 20: a 26-week controlled trial of efficacy and safety in the osteoarthritic knee. Clin Ther 1998;20:410-23.

15. Adams ME, Atkinson MH, Lussier AJ, Schulz JI, Siminovitch KA, Wade JP, et al. The role of viscosupplementation with hylan G-F 20 (Synvisc) in the treatment of osteoarthritis of the knee: a Canadian multicenter trial comparing hylan G-F 20 alone, hylan G-F 20 with non-steroidal anti-inflammatory drugs (NSAIDs) and NSAIDs alone. Osteoarthritis Cart 1995;3:213-25.

16. Lussier A, Cividino AA, McFarlane CA, Olszynski WP, Potashner WJ, De Medicis R. Viscosupplementation with hylan for the treatment of osteoarthritis: findings from clinical practice in Canada. J Rheumatol 1996;23:1579-85.

17. Disla E, Infante R, Fahmy A, Karten I, Cuppari GG. Recurrent acute calcium pyrophosphate dihydrate arthritis following intraarticular hyaluronate injection. Arthritis Rheum 1999;42:1302-3.

18. Maheu E. Hyaluronan in knee osteoarthritis: a review of the clinical trials with hyalgan. Eur J Rheumatol Inflamm 1995;15:17-24.

Frequently Asked Questions About HyaFlex™ and Hyaluronic Acid (HA)

IMPORTANT: All content of this website is provided for informational purposes only, and is not a substitute for professional medical advice. The products on this website are dietary supplements, not medication, and are not intended to diagnose, treat, cure, or prevent any disease or illness. Neither the products nor the content of this website have been subject to analysis or approval by the Food and Drug Administration. Should you suffer any side effects after ingesting these products, discontinue use and consult your licensed medical practitioner. These products are to be used in conjunction with, and not as a substitute for, a balanced, healthy diet and lifestyle. Please consult with your licensed medical practitioner if you have, or suspect you may have, a health problem. We will not be held responsible for any decision that you make regarding taking any products seen on this site.

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